ENGINEERING DESIGN & DEVELOPMENT
About Creative Orthopaedics
Creative Orthopaedics LLC is owned and operated by John R Pepper. After 19 years of corporate R&D experience, John founded Creative Orthopaedics to allow him to focus full time on the advanced stages of implant design. John's time as an experimental surgeon on a canine project funded by BioElectron taught many lessons of the reality of performing survival surgery. As a result, he has a unique appreciation of the challenges faced in the operating room.
'One of the World's Top 20 Trauma Innovators'
Orthopedic Intellectual Property Report as compiled by Medicine Lodge Inc. in 2001
Featured in New Haven Register on May 5, 2006, article titled, "Gadget Genius"
His CV is below:
John R. Pepper, M.S. P.E.
Master of Science Biomedical Engineering University of Texas Southwestern 1992
Bachelor of Science Mechanical Engineering Worcester Polytechnic Institute 1983
Professional Engineer Mechanical Engineering Commonwealth of Massachusetts
Principal Engineer/President – Creative Orthopaedics, LLC 2002- present
Specializing in concept generation, design and fabrication of orthopaedic implants and instruments in
close co-operation with forward thinking surgeons.
Surgeon Generated Concepts-Brought to Prototype stage
Numerous Neuro, Orthopaedic and Upper Extremity Surgeons
Market Evaluation and Research for Advisement for Company Purchase
Mid level spine company portfolio analysis
Senior Project Engineer – Doctors Research Group, 2001- 2002
Design of Self Contained Locking Orthopaedic Screw, 2.7mm, 3.5 mm and 4.0 mm
Senior Design Engineer -- Surgical Dynamics Division of US Surgical, 1999-2001
Designed Allograft Spacer & Instruments for Posterior Lumbar Spinal Fusion, now Stryker Allocraft
Combined requirements and constraints of surgeons, bone banks and intellectual property to make easy
to implant spacer system. Heavy surgeon interface.
Designed Stiffness Optimized Spinal Fusion Spacer Cage.
Extensive literature research to determine fundamental property of implants for fusion. Designed delivery
instruments with emphasis on ease of use and reducing OR time.
Evaluated patented technology for efficacy, all spacer cages. Researched novel material application to
spinal fusion market.
Full use of rapid prototyping to speed design iterations.
Virtual surgery performed on designs. Modeled anatomy, implant and instruments within CAD package.
Makes concepts easy to understand for surgeons and corporate personnel.
TriGen Design Engineer. Titanium nail system ~$100MM annual sales
TriGen is a comprehensive lower extremity fracture treatment system. Seven fracture classes are treated
with tools contained in one instrument case. A new entry and bone manipulation technique are the main
reason the TriGen system can reduce OR time by approximately thirty percent. Reception by hospital
staff and sales representatives has been outstanding. Primary design surgeons were Toney Russell, MD
and Roy Sanders MD. I was the main engineer on the team that developed the system. There are
numerous patents filed on designs for this, see the patent section.
See details at http://www.trigennails.com/
TriMax Design Engineer Modular Intramedullary Nail Clinical trial 1994-1996
TriMax is a modular Intramedullary nail designed to reduce inventory required to repair femoral neck and
shaft fractures. The Health Care market of the early nineties demanded a system that was going to cost
much less than the one piece nails used to that point. Over one hundred nails are implanted. Improvements
in the market place have halted full release of TriMax. Much instrumentation and several design features
were carried over to the TriGen system.
Conducted cadaver studies to justify design changes in the implant design. Full design responsibility.
Product, sales, and marketing support of existing products. Heavy surgeon interface.
Proven Ability: Innovative Product design.
Research Assistant -- University of Texas Southwestern and Humana Advanced Surgical Institutes,
Designed and carried out in vivo study of the effects of capacitive coupled electrical stimulation on limbs
lengthened by the Ilizarov technique. Lead surgeon for thirty four canine surgeries installing external
Spinal study of the effect of instrumentation on intradiscal pressure in conjunction with Texas Back Institute
Histology - determined cellular growth patterns in callus sections
Mechanical properties analysis using Instron testing machine
Assisted with craniofacial studies in porcine models
Proven Ability: Hands-on Surgical Experience - Medical Research - Publication
Mechanical Engineer -- Waters Chromatography Division of Millipore Corporation, 1985-1990
Designed Mechanical and Optical Design verification and testing hardware
Holographic mirror alignment fixture
Chromatography column burst pressure tester
Chromatography pump flow verification system
Tunable Ultraviolet Detector calibration test hardware
Inert Plumbing (PEEK) valve and pump test station
Modular printed circuit board docking station for test and calibration
Proven Ability: Mechanical Design - Prototyping - Production Support
Mechanical Engineer -- Hamilton Standard Div. of United Technologies, 1983-1985
Part of project management team responsible for testing and getting flight approval for an afterburner
fuel pump for the F15 and F16
Performed heat transfer study on instrumented hardware to optimize the weight of thermal insulation
features of the pump.
Tested pump cavity coatings to ensure performance with contaminated fluids
Strain gage testing to determine cause of field stress cracking of exhaust gas plenum
Electrical Technician / Junior Engineer -- John J. Pepper Corp. Corrosion Engineering Consultants,
Operating Room Protocol for Sales Representatives Sales Representative Training
Methodist University Hospital Smith Nephew
Memphis TN Internal course on products, OR protocol
5,489,284 Cannulated Modular Nail
5,549,610 Implant design for simultaneous treatment of femoral neck and shaft fracture
5,569,249 Cannulated Modular Intramedullary Nail
5,855,579 Cannulated Modular Intramedullary Nail
5,609,596 Guide rod manipulator - one hand operation allows faster fracture reduction
5,806,692 Apparatus for Storage and Display of Personal Communication Devices
5,951,561 Minimally Invasive Intramedullary Nail Insertion Instruments and Method
5,989,255 Orthopedic Bone Screw Apparatus
6,010,506 Intramedullary Nail Hybrid bow
6,183,477 Attachment Tool for Drill Guide
6,395,033 Dynamic Fusion Mechanostat Devices
6,620,167 Orthopedic Screw Having Driver-Locking Head
7,090,677 Surgical milling instrument for shaping a bone cavity
7,361,176 External bone/joint fixation device
7,407,483 Minimally invasive surgical access device
7,563,275 Bone Fixation implant system and method
20090259258 VERTEBRAL DISC TENSIONING DEVICE
20080287994 Pedicle Screw and Rod System
20080269567 SURGICAL ACCESS DEVICE ASSEMBLY
20080177331 Surgical Screw Including a Body that Facilitates Bone In-Growth
20080177329 Method for Providing Disc Regeneration Using Stem Cells
20080177328 Method for Vertebral Disc Annular Fibrosis Tensioning and Lengthening
20080177312 Interspinous Process Spacer Device
20080172128 Minimally Invasive Interbody Device Assembly
20080172127 Minimally Invasive Interbody Device
20080161931 Vertebral disc annular fibrosis tensioning and lengthening device
20080161822 Minimally invasive inter-spinous process spacer insertion device
20080125856 Bone Graft Delivery System for a Vertebral Interbody Device
20080125783 Disc space preparation device for spinal surgery
20070225665 Device for collecting bone material during a surgical procedure
20070219416 Minimally invasive surgical access device
20070043364 Spinal correction system with multi-stage locking mechanism
20060190021 Cutting device for subcutaneous incisions
20060015110 Cutting device
20050234459 Bone fixation implant system and method
20050149018 External bone/joint fixation device
20040236339 Long bone reaming apparatus and method
Effect of Capacitive Coupled Electrical Stimulation on Regenerate Bone
Journal of Orthopaedic Research, March 1996, 14:296-302; primary author
Minimally Invasive Surgery, An Engineering Approach
Orthopedic Design & Technology, Nov/Dec 2005, p30-35
The Design of Effective Orthopaedic Implants and Instruments. OMTEC, Orthopaedic Manufacturing and
Technology Exhibition and Conference, Chicago June 2005
Orthopaedics I, University of Memphis, 1995 & 1996,
Quinnipiac University, Sigma Xi Meeting, 2001
Studies (non published):
Intradiscal Pressure Measurements Above an Instrumented Fusion. A Cadaveric Study.
Weinhoffer SL, Guyer RD, Herbert M, Spine, March 1, 1995, 20 (5) p526-31; contributor; performed
initial cadaver study and data analysis; presented at society meeting
Implantable Drug Pump -- post mortem analysis of pump performance. Done in conjunction with the University
of Texas Southwestern Medical Center and the Denton County Coroner; presented at society meeting
Cadaveric Study of Intramedullary Canal Fill by Nails of Various Cross Section
Software Experience: SolidWorks, Unigraphics (1986-1999); Pro Engineer; Mechanica; Ansys, Access, SAS
Software In-House: SolidWorks Office (animation and rendering), Simulation FEA
In-House Manufacturing: South Bend Lathe, Bridgeport Mill, Wire Feed Welder, Compressed air, Drill Press, Polishing, Grinding, Heat Treat
Creative Orthopaedics LLC, 203.699.8475 and 203.510.6534